To unlock the following match types, complete the following.
To unlock the following venues, complete the following.
To unlock the following Characters, complete the following.
| Unlockable: | How to Unlock: |
| Baby Chris | Defeat Baby Chris at 7th Heaven in story mode. |
| Bless | Defeat Bless at Syn Energy Powerplant in story mode. |
| Bo | Defeat Bo at The Foundation in story mode. |
| Bone Crusher | Defeat Bone Crusher at 7th Heaven in story mode. |
| Bubba Sparxxx | Defeat Bubba Sparxxx at The Pit in story mode. |
| Carmen Electra | Defeat Carmen Electra with your girlfriend at The Babylon Club in story mode. Alternately, with Carmen Electra as your girlfriend win or lose to your ex-girlfriend at The Babylon Club. |
| Chiang | Defeat Chiang at The Dragon House in story mode. |
| Cindy J | With Cindy J as your girlfriend, defeat Nyne at The Babylon Club in story mode. |
| Comp | Defeat Comp at Syn Energy Powerplant in story mode. |
| Crazy Legs | Defeat Crazy Legs at The Terrordome in story mode. |
| Danny Trejo | Defeat Danny Trejo at The Limit in story mode. |
| Elephant Man | Defeat Elephant Man at The Babylon Club in story mode. |
| Erick Sermon | Defeat Erick Sermon at The Pit in story mode. |
| Fam Lay | Defeat Fam Lay at 7th Heaven in story mode. |
| Fat Joe as Crack | Defeat Crack at Club Murder in story mode. |
| Flava Flav | Defeat Flava Flav at The Terrordome in story mode. |
| Freeway | Defeat Freeway at Syn Energy Powerplant in story mod |
| Ice T | Defeat Ice T at Club 357 in story mode. |
| Joe Budden | Defeat Joe Budden at The Babylon Club in story mode. |
| Kimora | With Kimora as your girlfriend, defeat Nyne at The Babylon Club in story mode. |
| Lil Flip | Defeat Lil Flip at The Gauntlet in story mode. |
| Lil Kim | With Lil Kim as your girlfriend, defeat Nyne at The Babylon Club in story mode. |
| Ludacris | Defeat Ludacris at 7th Heaven: Club DTP in story mode. |
| Mack 10 | Defeat Mack 10 at The Chopshop in story mode. |
| Masa | Defeat Masa at The Dragon House in story mode. |
| Memphis Bleek | Defeat Memphis Bleek at The Limit in story mode. |
| Method Man as Blaze costume 2 | Successfully complete story mode. |
| Method Man as Blaze costume 3 | Successfully complete story mode. |
| N.O.R.E | Defeat N.O.R.E at The Heights in story mode. |
| Omar Epps as O.E. | Defeat O.E. at The Foundation in story mode. |
| Pockets | Defeat Pockets at The Babylon Club in story mode. |
| Prodigy | Defeat Prodigy at The Heights in story mode. |
| Rome | Defeat Rome at Syn Energy Powerplant in story mode. |
| Scarface | Defeat Scarface in The Babylon Club in story mode. |
| Sean Paul | Defeat Sean Paul at the Babylon Club in story mode. |
| Shaniqua | With any girlfriend, lose to Nyne at the Babylon Club in story mode. |
| Shawnna | With Shawnna as your girlfriend, defeat Nyne at The Babylon Club in story mode. |
| Slick Rick | Defeat Slick Rick at Syn Energy Powerplant in story mode. |
| Snoop Dogg as Crow | Defeat Crow at Crow's Office in story mode. |
| Solo | Defeat Solo at the Babylon Club in story mode. |
| Sticky Fingaz | Defeat Sticky Fingaz at Red Hook Tire Co. in story mode. |
| Sticky Fingaz: Costume 2 | Successfully complete story mode. |
| Teck | Defeat Teck at Hunt's Point Scrapyard in story mode. |
| Warren G | Defeat Warren G at The Chopshop in story mode |
| WC | Defeat WC at The Chopshop in story mode |
The following are the combinations of Martial Arts Styles.
| Unlockable: | How to Unlock: |
| Cruiserweight Style | Submission + Kickboxing + Wrestling |
| Drunken Kung Fu 1 | Martial Arts + Wrestling + Streetfighting |
| Drunken Kung-Fu 1 | Martial Arts + Streetfighting + Wrestling |
| Jeet Kune Do 1 | Martial Arts + Wrestling + Submission |
| Kung Fu 1 | Martial Arts + Submission + Kickboxing |
| Muay Thai Kixkboxing | Kixkboxing + Streetfighting + Wrestling |
| Street Brawl | Martial Arts + Kickboxing + Wrestling |
| Street Brawl 1 | Martial Arts + Streetfighting + Kickboxing |
| Street Brawl 1 | Martial Arts + Kickboxing + Streetfighting |
| Street Brawl 2 | Martial Arts + Wrestling + Kickboxing |
| Street Brawl 3 | Martial Arts + Streetfighting |
| Street Brawl 4 | Martial Arts + Kickboxing |
| Technical Freak | Martial Arts + Submission |
| Tiger Claw 1 | Martial Arts + Submission + Streetfighting |
| Tiger Claw 1 | Martial Arts + Streetfighting + Submission |
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