| Unlockable: | How to Unlock: |
| Broken Hearted (80 GP) | Complete Case 1: Broken Hearted. |
| Chemistry Master (20 GP) | Identify the chemical for Riley in Case 2. |
| Cinephile (5 GP) | Watch a movie from a case file. |
| Coulda Been a Contender (80 GP) | Complete Case 2: Coulda Been a Contender. |
| Crime Scene Impersonator (80 GP) | Complete Case 5: Crime Scene Impersonator. |
| CSI: Deadly Intent (100 GP) | Completed all five cases of CSI: Deadly Intent. |
| Deadly Secret (35 GP) | Identify the makeup worn by the victim. |
| DNA Master (20 GP) | Identify the DNA for Juarice Briggs in Case 3. |
| Document Master (20 GP) | Identify the Document for Nick in Case 4. |
| Enhanced Interrogation Technique (25 GP) | Obtain at least an 80% cunning score in one case. |
| Extinguished (80 GP) | Complete Case 4: "Extinguished". |
| Fastidious (25 GP) | Obtain at least a 90% thoroughness score in one case. |
| Fingerprint Master (20 GP) | Identify the fingerprint for Dr. Langston in Case 1. |
| Gearhead (5 GP) | View the Options screen. |
| Good Cop (10 GP) | Obtain at least a 65% cunning score in one case. |
| Heart Mender (35 GP) | Reassemble heart-shaped ashtray in Case 1. |
| Keeping up with the Hodges (25 GP) | Earn at least an 80% skill score in one case. |
| Lab Rat (10 GP) | Earn at least a 65% skill score in one case. |
| Last Gasp (80 GP) | Complete Case 3: "Last Gasp". |
| Master Inquisitor (40 GP) | Obtain a 100% cunning score in one case. |
| Master Technician (40 GP) | Earn a 100% skill score in one case. |
| Meticulous (40 GP) | Obtain a 100% thoroughness score in one case. |
| Observant (10 GP) | Obtain at least a 65% thoroughness score in one case. |
| Strong Reader (5 GP) | Visit a case file. |
| Touch of the Irish (35 GP) | Collect all the bottles of Classic Cork. |
| We Love CSI Fans! (5 GP) | Watched the opening to CSI: Deadly Intent. |
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CSI: Deadly Intent Items
