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Answer from: ThrillFyMe
Destroy the Savato web 3 times, then use laser on savato. As the Savato's outer coat is getting thinner, inject the black serum (Sidney and Victor will give you this on the cutscene) and repeat (I think) until it creates 8 laceration on the heart after that use the healing touch 2 times. Don't use healing touch Until this point. Then you defeat it.